Imbalance of Genes Encoding Natural Killer ImmunoglobulinLike Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer

publicaciones

We performed combined multidimensional characterization of genes that encode KIRs and their ligands in blood samples from patients with BDC from Sweden, followed for up to 8 years after diagnosis (n ¼ 148), in 2 geographically matched cohorts of healthy individuals from Northern Europe (n ¼ 204 and n ¼ 900), and in healthy individuals from 6 geographically unrelated populations (n ¼ 2917). We used real-time polymerase chain reaction, RNA sequencing, immunohistochemistry, and flow cytometry to evaluate NK-cell presence, as well as KIR and KIR-ligand expression in bile duct tumors and control tissues.

2019 2 Imbalance of Genes Encoding Natural Killer ImmunoglobulinLike Receptors and Human Leukocyte Antigen in Patients With-1


COMPARTE