Evaluation of the Coating with TiO2 Nanoparticles as an Option for the Improvement of the Characteristics of NiTi Archwires: Histopathological, Cytotoxic, and Genotoxic Evidence


For the EPD, diferent voltages and diferent times were used. Male rats were used in four groups (�=3) with diferent treatments.
Te blood sample was obtained for genotoxic analysis and liver and kidney organs were removed for histopathological analysis. Teamount of NPs TiO2 deposited on the samples of the arches increases gradually in the times of 15 and 30 s. At all voltages, however, at 45, 60, 75, and 90 s, there is an increase up to 25 V. Cell viability in lymphocytes treated with TiO2 NPs did not cause genotoxicity.
In the histopathological fndings of hepatic and renal tissue, nuclear alterations and necrosis were observed. Te objective of the
study was to improve the physical and biocompatibility characteristics of the NiTi arches for which the EPD is used. Te technique for the deposition of TiO2 NPs was used, where this technique could be used as an economical and versatile way to perform homogeneous depositions even on surfaces with the complexity of the NiTi alloy. As for genotoxicity and cytotoxicity, we continue to have controversial results.

2018 NPS Tio2