Evaluación del potencial antineoplásico y citotóxico de metabolitos de Solanum elaeagnifolium, mediante ensayos biodirigidos por el modelo de Artemia salina

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Facultad de Ciencias Químicas

QFB Leobardo Hernández Ocura

Abstract: Solanaceae have high anticancer potential, there is no scientific documentation to validate the use of Solanum elaeagnifolium as an antineoplastic agent, it is has been used for years in artisanal cheesemaking. According to the above in this paper evaluation of the cytotoxic activity of the compounds of S. elaeagnifolium on Artemia salina, neoplastic tissues and Vero, HeLa and MCF-7 cell lines was proposed. The FCLV7 fraction tested on cell lines showed greater effect on cervical cancer cell line (HeLa) also showed higher activity on breast tumor tissue. We also found that there is a specific partial correlation between the activity showed on tested cell lines and tumor tissue of the patient in remission with the fractions tested.

Thesis Leobardo Hernández Ocura


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