Bacterial resistance challenged by binary antimicrobial combinations


N.M. De la Fuente-Salcido*, D. López-De la Cruz and A. Alejo Andrade

Bioprospecting and bioprocessing, Autonomous University of Coahuila, Blvd, Torreón-Matamoros Km. 7.5. 27276, Coahuila, México.

Resistance or multi-resistance to antibiotics by microorganisms has generated one of the most emerging problems of public health due to the loss of susceptibility to drugs. The World Health Organization (WHO) publishes the groups of bcteria considered antibiotic-resistant “priority pathogens”, and for these microbes new antimicrobials of strategic combinations are urgently needed. A novel strategy to control resistance is the application of combined antimicrobials with synergestic effect to destroy priority pathogens, but also against parasites, fungi, even viral particles. Therefore, it is importnt to expand the scientific knowledge regarding to antimicrobial combinations and the pharmacological treatments to preserve human health because paradoxically, the former solution to the spread of infectious diseases found in antibiotics, is now the main cause of a new problema: antimicrobial resistance.